RESEARCH AREA

Glioblastoma Multiforme (GB)

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Completed Trials

2017: Avelumab in patients with newly diagnosed GBM (Phase II)

Future Trial

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Neuromuscular

Neuromuscular diseases encompass pathologies of the peripheral nerves (diabetic peripheral neuropathy, CIDP), neuromuscular junction (myasthenia gravis) and muscles (myositis, muscular dystrophy).

At CNO

Symptoms can consist of weakness, numbness, tingling, pain, double vision, drooping eyelids, difficulty swallowing, difficulty walking or climbing stairs. Neuromuscular diseases are investigated using EMG/NCS, ultrasound, MRI, blood tests and genetic testing. Treatmetns vary according to the underlying disease mechanism.

We evaluate such conditions with a clinical evaluation, electrophysiological tests such as EMG, NCS, SFEMG and neuromuscular ultrasound.


Treatment of various neuromuscular conditions often involves prescriptions medications, some of which can be administered at our onsite infusion clinic.

We also offer the receiving of possible experimental treatments via our clinical trial department and rehabilitation services via our Neurorehabilitation section.

Carpal tunnel Syndrome is a very common neuromuscular condition where the median nerve is compressed at the wrist, thus leading to intermittent tingling and numbness of the hand(s).

CNO evaluates Carpal Tunnel Syndrome with a clinical evaluation, EMG/NCS and Ultrasound.

Once the diagnosis is confirmed, patients are referred to the CNO’s plastic surgeon (hand specialist) who will discuss the surgical treatment options with the patient.
CNO offers a multidisciplinary approach to patients with GBM. Our neurologists in conjunction with other specialists; oncologists and neurosurgeons are involved in the diagnosis and medical treatment of the tumor and its complications such as seizures, our patients benefit from personalized neurorehabilitation through our in-house NeuroGym rehabilitation program, designed to help improve motor deficits affecting ambulation.
CNO is currently looking at using non invasive neuromodulation (NNIM) via repetitive transcranial magnetic stimulation (rTMS) to improve outcomes in patients with GBM.
Experimental treatments can be accessed via our clinical trials. CNO previously initiated and conducted a clinical trial which looked at combining immunotherapy with conventional therapies.