RESEARCH AREA

Multifocal Motor Neuropathy

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Clinical Trial - Recruiting

ARGX-117-2302 Empassion (argenx)

For more information contact Victorine Sikati Foko Recruitment will start in few next weeks

Completed Clinical Trials

2023 BIAL (Phase II)
2021: BN42358 study (Phase IIb)
2014: iSTEP study (Phase III)
2011: CONFIDENT-PD study (Phase II)
2010: AFQ056A2217 study (Phase II)
2010: AFQ056A2208 study (Phase II)

Symptoms & Cause

Symptoms generally develop slowly over years. The progression of symptoms is often a bit different from one person to another due to the diversity of the disease. People with PD may experience:

Tremor, mainly at rest and described as pill-rolling tremor in hands. Other forms of tremor are possible

The cause remains largely unknown. Although there is no cure, treatment options vary and include medications and surgery. While Parkinson’s itself is not fatal, disease complications can be serious.

Diagnose & Treatment

There is no “one way” to diagnose Parkinson’s disease (PD). However, there are various symptoms and diagnostic tests used in combination. Making an accurate diagnosis of Parkinson’s — particularly in its early stages — is difficult.

There is no standard treatment for Parkinson’s disease (PD). Treatment for each person with Parkinson’s is based on his or her symptoms. Treatments can include medications, physical therapy, surgical options, medical marijuana, clinical trials, lifestyle modifications, like getting more rest and exercise.

There are many medications available to treat Parkinson’s symptoms, although none yet that reverse the effects of the disease. It is common for people with PD to take a variety of these medications — all at different doses and at different times of day — to manage symptoms.

Importance of clinical research

Scientists and doctors are working together to find a treatment or prevention technique. The clinical research will help to attract the attention of the federal and state government as well as the pharmaceutical industry to the growing need and urgency in addressing PD. This is an important first step to better understanding who develops PD and why. We participate in a number of clinical trials aiming to create advancements for the treatment of Multiple SclerosisStrokeParkinson’sAlzheimer’s and Glioblastoma Multiforme (GBM). Our participation allows us to offer many treatments long before they become available to a majority of specialists, giving patients an opportunity to choose from a wide range of care that, while experimental in nature, may possibly be more effective. Cutting edge treatments aren’t the only reason we conduct clinical trials, nor are they the only reason patients decide to participate. Our involvement gives us the opportunity to develop better protocols and, most importantly, to help advance the treatments themselves. When it comes to Neurological diseases, large strides have been made in recent years; results that would have been impossible without the participation of Doctors, Nurses and, most of all, patients.

Multifocal Motor Neuropathy

Multifocal Motor Neuropathy (MMN) is a rare autoimmune disease affecting peripheral motor nerves. It is manifested by slowly progressive painless asymmetrical weakness of hand and/or legs without any sensory loss.

Clinical Trials

Treatment with Intravenous Immunoglobulins IVIG will improve symptoms and significantly slow the disease progression.

Research for alternative treatments is ongoing. CNO is involved in clinical trials testing new therapies (complement inhibitors) for MMN.

Studies Recruiting

ARGX-117-2302 Empassion (argenx)

Target Population: Men and women over 18 with a diagnosis of MMN that satisfies the European diagnostic criteria of 2010.
For more information contact Victorine Sikati Foko.

Studies Ongoing

Currently, there are no ongoing studies being conducted.

Completed studies

No available completed studies.